Venus Williams was upset by Agnieszka Radwanska 6-3, 6-0 Thursday at the Fortis Championships, losing in her second match back after missing nearly three months with a wrist injury.
The 95th-ranked Radwanska of Poland will take on top-seeded Elena Dementieva of Russia in the quarter-finals. The 54th-ranked Williams beat Ana Ivanovic on Wednesday in her first match since Wimbledon.
In other matches, Nathalie Dechy defeated second-seeded Nadia Petrova 6-4, 6-3 and will meet Alona Bondarenko, who beat Katarina Srebotnik 4-6, 6-4, 6-3.
Fifth-seeded Francesca Schiavone advanced with a 6-2, 6-1 win over Roberta Vinci and will face Patty Schnyder.