Atkins homered twice and drove in four runs, and he has 10 RBIs in his last two games, including the Rockies' 20-8 win over the Giants on Monday. Holliday's homer to left in the third travelled 478 feet, the longest at Coors this season.

Barry Bonds' run-scoring single in the third gave him 1,922 RBIs, tying Jimmie Foxx for fifth place on the all-time list. Bonds was 2-for-4 with a walk, but hit an inning-ending flyout with the bases loaded in the eighth off Jeremy Affeldt, who got his first save since Sept. 22, 2004.

Jason Jennings (9-12) allowed three runs and seven hits in five innings.

Cain, who had given up one earned run in his prior 42 innings, allowed seven runs and 11 hits in 5 1-3 innings.